PolyPhil® is an advanced bioregenerative product based on highly purified polynucleotides (PN-HPT® – Highly Purified Technology), intended to improve skin quality, support tissue regeneration, and repair processes at the cellular level.

It is not a classic filler or a skinbooster—its action is biological and vasculotropic/regenerative, without a volumizing effect.

Mechanism of action

Polynucleotides contained in PolyPhil®:

• stimulate fibroblast activity,
• support collagen and elastin synthesis,
• improve cellular metabolism,
• protect cellular DNA,
• have vasculotropic effects—improving microcirculation and tissue perfusion.

As a result, the product improves the skin microenvironment, supporting regeneration and rebuilding.

Clinical indications

PolyPhil® may be used for:

• decreased skin quality and elasticity,
• thin, dehydrated skin,
• tired, hypoxic skin,
• early to moderate signs of aging,
• impaired cutaneous microcirculation,
• skin requiring regeneration after technology-based procedures.

It works particularly well:

• in skin-quality therapies,
• for patients avoiding volumization,
• as support for healing and regeneration processes.

Treatment areas

• face (especially thin-skin areas),
• eye area,
• neck,
• decolletage,
• hands,
• scalp (in selected protocols).

Treatment course

• performed after medical qualification,
• administered intradermally or subcutaneously,
• therapy is staged and effects build gradually.

The treatment plan is individualized depending on skin quality and therapeutic goals.

Treatment outcome

• improved skin quality and density,
• increased elasticity and tension,
• improved tone and microcirculation,
• smoothing of fine irregularities,
• natural regenerative effect without changing facial features.

Effects develop according to the biological tissue-regeneration cycle.

Combination therapy options

PolyPhil® may be used:

• as a standalone therapy,
• combined with other polynucleotides,
• as support after Endolift®, RF and HIFU,
• in regenerative and anti-aging protocols,
• as part of long-term skin-quality therapy.

Medical information

PolyPhil® treatment is performed only after a medical consultation. The product works through biological regeneration and improved microcirculation rather than mechanical filling.

PolyPhil® is a next-generation polynucleotide aimed at improving skin quality and regenerative capacity at the cellular level.